Beijing University of Chemical Technology researchers found that the virus was comparable to Sars-CoV-2, which was identified in pangolins before the Covid-19 pandemic in 2017.
Researchers in China are working with a lethal virus that kills mice 100% of the time. The deadly virus, named GX_P2V in a study published on bioRxiv, attacked mice whose genomes were engineered to mimic human genetic makeup. Within five days of infection, the mice became lethargic, lost a significant amount of weight, and developed white eyes, according to the researchers. The researchers added in the paper that they passed away only eight days after contracting the infection.
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The experts were taken aback by how quickly people were dying with this virus.
After studying the mice’s bodies, they discovered that the virus had affected the brains, tracheas, eyes, lungs, and bones. The researchers concluded that the animals died as a result of severe brain illness. Beijing University of Chemical Technology researchers found that the virus was comparable to Sars-CoV-2, which was identified in pangolins before the COVID-19 pandemic in 2017. Beyond the previously published results from a different study, the research team stated in the paper that it is the first of its type to reveal a 100% mortality rate in mice infected by the coronavirus-related virus.
Importantly, the study’s findings do not indicate how this virus might impact people.
Specialists voiced concerns as soon as the study was posted online. Expert in epidemiology at the Genetics Institute at University College London, Francois Balloux, denounced the study as “horrible” and “scientifically pointless.” I fail to see anything remotely interesting that could be discovered by randomly introducing a random virus into a strange breed of humanized mice. However, I could see how things like that may go awry,” he stated on X (previously Twitter). Despite being the epicenter of lab leak speculations concerning the pandemic, the Wuhan Institute of Virology in China does not appear to have any affiliation with the 2024 study.
According to an unpublished study, researchers in China are testing a mutant strain of COVID-19 virus that can kill 100% of “humanized” mice.
The virus, known as GX_P2V, killed all of the human ACE2-transgenic mice, possibly as a result of a late-stage brain infection, according to a paper that was posted on the preprint site bioRxiv and hasn’t been reviewed yet. Researchers from Nanjing University in China and the University of Chemical Technology conducted a study that revealed GX_P2V attacked the brains of mice whose genetic composition was modified to resemble that of humans. The researchers stated in the publication that “this highlights a spillover risk of GX_P2V into humans and provides a unique model for understanding the pathogenic mechanisms of SARS-CoV-2-related viruses.”
A mutated form of GX/2017, a coronavirus relative that was purportedly found in Malaysian pangolins in 2017 — three years before the pandemic — is what causes the deadly GX_P2V Infection. According to the New York Post, researchers observed that all of the virus-infected mice died within eight days, a “surprisingly” quick death rate.
The investigation revealed that GX_P2V had infected the dead mice’s tracheas, eyes, lungs, bones, and brains—the last of which was serious enough to be the final factor in the animals’ demise. The mice had rapidly lost weight, had a stooped posture, and walked incredibly slowly a few days before they died. According to the story, the day before they passed away, even their eyes turned entirely white.
The study was criticized by experts as “horrible” and “scientifically pointless.” about the virus
“I don’t see anything remotely interesting that could be discovered by randomly infecting a strange breed of humanized mice with a random Infection. On the other hand, I could see how much might go wrong,” Francois Balloux, an expert in epidemiology at the Genetics Institute of University College London, wrote in a piece on X.com.
